FERJI Khalid | lcpm.univ-lorraine.fr

Statut

Maitre de conférences

Mots clés

Polymer chemistry; Polymer self-assembly; Polymerization-Induced self-assembly (PISA); Photo-polymerization

physical-Chemistry

Drug Delivery

Axes et thématiques

**Photo-Polymerization induced self-assembly**

**Encapsulation of QDs in photo-cross-linked micelles**

**Smart nanocarriers for drug delivery**

Education and experience:

Recently, I have developed a strong interest in applying artificial intelligence and machine learning techniques to automate polymer synthesis and predict their physicochemical properties.

I received my PhD in polymer chemistry in 2013 from the University of Lorraine, where I mastered the art of (co)polymer design. From 2013 to 2014, I joined the IMMM (University of Maine) as a postdoctoral researcher, where I gained extensive experience in colloid science and light scattering techniques. Seeking to broaden my expertise at the interface of macromolecules and biomedicine, I moved to LCPO (University of Bordeaux) for a second postdoctoral fellowship. Over the course of 18 months, I worked on the self-assembly of copolymers and lipids to produce biomimetic vesicles, which can serve as nanocarriers for drug/gene delivery and as cell models.

Currently, I am Associate Professor at ENSIC and a researcher at LCPM. I obtained my Habilitation to Supervise Research (HDR) in 2022, focusing on the preparation of polysaccharide-based nano-objects using the photo-RAFT Polymerization-Induced Self-Assembly (photo-RAFT PISA) methodology.

Teaching and administrative activities:

Polymer Science and organic synthesis at different levels (Bachelor and Master), mainly at two Schools of Engineers (ENSIC and EEIGM) - Lorraine University.

Pedagogical coordinator of the Master program "Products Environment Resources Energy (PERSEE)"

Research activity:

Design and formulation of colloids and nano-objects via in-situ Polymerization Induced Self-Assembly (PISA).
Macromolecular engineering using controlled radical polymerization techniques (ATRP, RAFT, PET-RAFT, photo-RAFT).
Integration of machine learning and AI-guided optimization in polymer synthesis and self-assembly processes.
Chemical modification of polysaccharides and synthesis of functional glycopolymers.
Development of stimuli-responsive polymers (pH, light, thermal, and redox sensitive systems).
Physical-chemistry of self-assembly (light scattering techniques) and design of amphiphilic macromolecules.
Applications in therapeutic nanotechnologies, drug delivery systems, and biomaterials.
Organic synthesis related to monomers, functional polymers, and polymeric materials.

<Watch a photo-PISA in water>

Memberships, editorial and review activities:

- French Polymer Group (GFP). President of the East section (2022-...).

- French Chemical Society (SCF).

- Advisory Board of Polymers.

- Guest Editor for Polymers, special issue “Polymerization-Induced Self-Assembly, PISA” (2021).

- Guest Editor for Polymers, special issue “Glycopolymers and Polysaccharide-based Copolymers” (2019).

- Referee for many scientific journals: https://publons.com/researcher/1324992/khalid-ferji/

- Expert for French National Research Agency (2022), ACS Petroleum Research Fund (2021) and Czech Academy of Sciences (2020).

Selection of recent publications:


A36-	K. Ferji, (DetectNano: Deep Learning Detection in TEM Images for High-Throughput Polymer Nanostructure Characterization), 2025. https://doi.org/10.26434/chemrxiv-2025-qxp7x*
A35-	K. Ferji, (Basic Concepts and Tools of Artificial Intelligence in Polymer Science) Polymer Chemistry, 2025. https://doi.org/10.1039/D5PY00148J*
A34-	E. P. F. Parra, J-L. Six and K. Ferji*, Polymer Chemistry, 2025,16, 994-1002. https://doi.org/10.1039/D4PY01076K
A33-	E. P. F. Parra, j. Oumerri, A. A. Andrea, J-L. Six, S. P. Armes, K. Ferji, Macromolecules, 2025*, 58, 1, 61–73. https://doi.org/10.1021/acs.macromol.4c01772
A32-	A. Khalil, C. M. Lopez, F. C. Pérez-Martínez, C. Gerardin-Charbonnier, K. Ferji, C. A. Moreno, J-L. Six, European Polymer Journal 2024, 113022. https://doi.org/10.1016/j.eurpolymj.2024.113022
A31-	J. Oumerri, H. Qayouh, A. A. Arteni, J‐L. Six, M. Lahcini, K. Ferji,ChemPhysChem* 2024, e202400291. https://doi.org/10.1002/cphc.202400291
A30-	Y. El Halmouch, H. AH Ibrahim, N. M Dofdaa, M. EM Mabrouk, M.-M. El-Metwally, T. Nehira, K. Ferji, Y. Ishihara, K. Matsuo, M. IA Ibrahim, Carbohydrate Polymers 2023, 311, 120743. https://doi.org/10.1016/j.carbpol.2023.120743
A29-	D. Ikkene, J-L. Six, K. Ferji, European Polymer Journal* 2023, 111848.https://doi.org/10.1016/j.eurpolymj.2023.111848
A28-	Z. Ferjaoui, S. Nahle, R. Schneider, H. Kerdjoudj, D. Mertz, F. Quilès, K. Ferji, E. Gaffet, H. Alem, Advanced Materials Interfaces 2023, 10, 2202364. https://doi.org/10.1002/admi.202202364.
A27-	D. Ikkene, A. A. Arteni, C. Boulogne, J.-L. Six, and K. Ferji, Macromolecules*2022, 55, 11, 4268. https://doi.org/10.1021/acs.macromol.2c00561.
A26-	M. Er-Rafik, K. Ferji,** J. Combet, O. Sandre, S. Lecommandoux, M. Schmutz, J-F. Le Meins, C. M. Marques, Soft Matter, 2022*,18, 3318. https://doi.org/10.1039/D2SM00179A.
A25-	D. L. Buitrago-Rincon, V. Sadtler, R. A. Mercado, T. Roques-Carmes, L. Benyahia, A. Durand, K. Ferji, P. Marchal, J. A. Pedraza-Avella, C. Lemaitre, Nanomaterials 2022, 12(11), 1906. https://doi.org/10.3390/nano12111906.
A24-	M. A. I. Al-Hatamleh, W. Alshaer, M. M. Hatmal, L. Lambuk, N. Ahmed, M. Z. Mustafa, S. C. Low, J. Jaafar, K. Ferji, J-L. Six, V. Uskoković and R. Mohamud, Frontiers in Molecular Biosciences 2022, 9, 865833. https://doi.org/10.3389/fmolb.2022.865833.
A23-	V. L. Romero Castro, B. Nomeir, A.A. Arteni, M. Ouldali, J-L. Six, *K. Ferji,** Polymers 2021, 13, 23, 4064. https://doi.org/10.3390/polym13234064.
A22-	D. Ikkene, A.A. Arteni, M. Ouldali, G. Francius, A. Brûlet, J-L. Six and *K. Ferji,** Biomacromolecules, 2021, 22, 7, 3128–3137. https://doi.org/10.1021/acs.biomac.1c00569.
A21-	A. Khalil, C. Gerardin-Charbonnier, H. Chapuis, K. Ferji, J.-L. Six, ACS Sustainable Chemistry & Engineering, 2021, 9, 34, 11458–11468. https://doi.org/10.1021/acssuschemeng.1c03607.
A20-	K. Perumal, S. Ahmad, M.-H. Mohd-Zahid, W.-N. Wan Hanaffi, Iskander ZA, J.-L. Six, K. Ferji, J. Jaafar, J.-C Boer, M. Plebanski, V. Uskoković, R. Mohamud, Frontiers in Nanotechnology, 2021, 3, 681760. https://doi.org/10.3389/fnano.2021.681760
A19-	E. P. Fonseca Parra, B. Chouchene, J-L. Six, R. Schneider, and *K. Ferji,** ACS Applied Polymer Materials, 2021, 3, 7, 3649. https://doi.org/10.1021/acsapm.1c00586.
A18-	M. El Founi, H. Laroui, B. S.B. Canup, J. S. Ametepe, R. Vanderesse, S. Acherar, J. Babin, K. Ferji, I. Chevalot, and J-L Six, ACS Applied Bio Materials, 2021, 4, 3, 2742. https://doi.org/10.1021/acsabm.0c01644.
A17-	M. AI Al-Hatamleh, M H. Ma’mon, W. Alshaer, EA Rahman, H. Mohd-Zahid, D. M Alhaj-Qasem, C. Yean, I. Z Alias, J. Jaafar, K. Ferji, J-L. Six, V. Uskoković, H. Yabu, R. Mohamud, European Journal of Pharmacology, 2021, 896, 5, 173930. https://doi.org/10.1016/j.ejphar.2021.173930.
A16-	D. Ikkene, A.A. Arteni, M. Ouldali, J-L. Six and *K. Ferji,** Polymer Chemistry, 11, 2020, 4729. https://doi.org/10.1039/D0PY00407C.
A15-	M, Nguyen, K. Ferji, S. Lecommandoux and C. Bonduelle, Polymers. 12, 41, 2020, 1357. https://doi.org/10.3390/polym12061357.
A14-	P. Lertturongchai, M. I. A. Ibrahim, A. Durand, P. Sunintaboon, and *K. Ferji,**Macromol. Rapid Commun. 41, 2020, 2000058. https://doi.org/10.1002/marc.202000058.
A13-	D. Ikkene, A.A. Arteni, H. Song, H. Laroui, J-L. Six and *K. Ferji,** Carbohydrate polymers, 234, 2020, 115943. https://doi.org/10.1016/j.carbpol.2020.115943.
A12-	M. Al-Hatamleh, E. A. R Nur Syafirah, J.C Boer, K. Ferji, J.L. Six, X. Chen, E. Elkord, M. Plebanski and R. Mohamud, Cells, 9(1), 2020, 33.https://doi.org/10.3390/cells9010033.
A11-	B. Nomeir, O. Fabre and *K. Ferji,** Macromolecules, 52, 2019, 6898. https://doi.org/10.1021/acs.macromol.9b01493.
A10-	S. Soliman, M. El Founi, R. Vanderesse, S. Acherar, K. Ferji, J. Babin, and J-L. Six, Colloids and Surfaces B: Biointerfaces, 182, 2019, 110393.https://doi.org/10.1016/j.colsurfb.2019.110393.
A09-	J.L. Six, K. Ferji,* Polymer Chemistry, 2019,10, 45. https://doi.org/10.1039/C8PY01295D.
A08-	A. Roy, A. Valderrama, V. Daujat, K. Ferji, M. Léonard, A. Durand, J. Babin, and J-L. Six, Journal of Materials Chemistry B, 6, 2018, 5130. https://doi.org/10.1039/C8TB01255E.
A07-	K. Ferji,* P. Venturini, F. Cleymand, C. Chassenieux and J.-L. Six, Polymer Chemistry, 9, 2018, 2868. (front cover). https://doi.org/10.1039/C8PY00346G.
A06-	T. P. Dao, F. Fernandes, E. Ibarboure, K. Ferji, M. Prieto, O. Sandre, J-F. Le-Meins, Soft Matter, 13, 2017, 627. https://doi.org/10.1039/C6SM01625A.
A05-	T. P. Tuyen Dao, A. Brûlet, F. Fernandes, M. Er-Rafik, K. Ferji, R. Schweins, J.-P. Chapel, A. Fedorov, M. Schmutz, M. Prieto, O. Sandre, and J.-F. Le Meins, Langmuir, 33, 2017, 1705. https://doi.org/10.1021/acs.langmuir.6b04478.
A04-	K. Ferji, I. Hamouda, C. Chassenieux, B. Nadal, B. Dubertret, C. Gaillard, E. Nicol. Journal of Colloid and Interface Science, 476. 2016, 222, https://doi.org/10.1016/j.jcis.2016.05.031.
A03-	A. Peyret, J.F..Trant, C. Bonduelle, K. Ferji, N. Jain, S. Lecommandoux, E.R. Gillies, Polymer Chemistry, 6, 2015, 7902. https://doi.org/10.1039/C5PY01060H.
A02-	K. Ferji, C. Nouvel, J. Babin, M.H. Li, C. Gaillard, E. Nicol, C. Chassenieux, J-L. Six, ACS Macro Letters 4, 2015, 1112. https://doi.org/10.1021/acsmacrolett.5b00471.
A01-	K. Ferji, C. Nouvel, J. Babin, P.A. Albouy, M.H. Li, J-L. Six, Journal of Polymer Science Part a-Polymer Chemistry 51, 2013, 3829. https://doi.org/10.1002/pola.26804.