| Titre | Helical oligomers of thiazole-based γ-amino acids: synthesis and structural studies. |
| Publication Type | Journal Article |
| Year of Publication | 2013 |
| Authors | Mathieu, L, Legrand, B, Deng, C, Vezenkov, L, Wenger, E, Didierjean, C, Amblard, M, Averlant-Petit, M-C, Masurier, N, Lisowski, V, Martinez, J, Maillard, LT |
| Journal | Angew Chem Int Ed Engl |
| Volume | 52 |
| Issue | 23 |
| Pagination | 6006-10 |
| Date Published | 2013 Jun 3 |
| ISSN | 1521-3773 |
| Abstract | 9-Helix: 4-Amino(methyl)-1,3-thiazole-5-carboxylic acids (ATCs) were synthesized as new γ-amino acid building blocks. The structures of various ATC oligomers were analyzed in solution by CD and NMR spectroscopy and in the solid state by X-ray crystallography. The ATC sequences adopted a well-defined 9-helix structure in the solid state and in aprotic and protic organic solvents as well as in aqueous solution. |
| DOI | 10.1002/anie.201302106 |
| Alternate Journal | Angew. Chem. Int. Ed. Engl. |
| PubMed ID | 23619818 |