Titre | Consequences of isostructural main-chain modifications for the design of antimicrobial foldamers: helical mimics of host-defense peptides based on a heterogeneous amide/urea backbone. |
Publication Type | Journal Article |
Year of Publication | 2010 |
Authors | Claudon, P, Violette, A, Lamour, K, Decossas, M, Fournel, S, Heurtault, B, Godet, J, Mély, Y, Jamart-Grégoire, B, Averlant-Petit, M-C, Briand, J-P, Duportail, G, Monteil, H, Guichard, G |
Journal | Angew Chem Int Ed Engl |
Volume | 49 |
Issue | 2 |
Pagination | 333-6 |
Date Published | 2010 |
ISSN | 1521-3773 |
Mots-clés | Amides, Anti-Infective Agents, Candida, Cell Membrane, Drug Design, Escherichia coli, Microbial Sensitivity Tests, Microscopy, Immunoelectron, Molecular Conformation, Molecular Mimicry, Peptides, Protein Folding, Protein Structure, Secondary, Pseudomonas aeruginosa, Staphylococcus aureus, Structure-Activity Relationship, Urea |
DOI | 10.1002/anie.200905591 |
Alternate Journal | Angew. Chem. Int. Ed. Engl. |
PubMed ID | 19957258 |