Titre | Synthesis of water-soluble and water-insoluble amphiphilic derivatives of dextran in organic medium. |
Publication Type | Journal Article |
Year of Publication | 2013 |
Authors | Covis, R, Ladaviere, C, Desbrieres, J, Marie, E, Durand, A |
Journal | Carbohydr Polym |
Volume | 95 |
Issue | 1 |
Pagination | 360-5 |
Date Published | 2013 Jun 5 |
ISSN | 1879-1344 |
Mots-clés | Catalysis, Dextrans, Dimethyl Sulfoxide, Epoxy Compounds, Quaternary Ammonium Compounds, Solubility, Solvents, Viscosity, Water |
Abstract | Hydrophobically modified dextrans were prepared by reacting native polysaccharide with 1,2-epoxydodecane in dimethylsulfoxide. Epoxide oligomerization was shown to occur as a secondary reaction when hydroxide ions were used as base catalysts. By adjusting the amount of epoxide in the feed, dextran derivatives with degrees of substitution (DS) between 0% and 164% were obtained. Polymers with DS above 100% were readily soluble in organic solvents like tetrahydrofuran, dioxane and water-saturated chloroform and dichloromethane. Their solution properties in organic solvent were characterized by capillary viscometry. Water-soluble derivatives were compared to other amphiphilic dextrans obtained using a heterogeneous modification in aqueous medium. The effect of modification conditions on substitution pattern was evidenced. |
DOI | 10.1016/j.carbpol.2013.03.010 |
Alternate Journal | Carbohydr Polym |
PubMed ID | 23618280 |