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(S)-ABOC: a rigid bicyclic β-amino acid as turn inducer.

Titre(S)-ABOC: a rigid bicyclic β-amino acid as turn inducer.
Publication TypeJournal Article
Year of Publication2012
AuthorsAndré, C, Legrand, B, Deng, C, Didierjean, C, Pickaert, G, Martinez, J, Averlant-Petit, MChristine, Amblard, M, Calmes, M
JournalOrg Lett
Volume14
Issue4
Pagination960-3
Date Published2012 Feb 17
ISSN1523-7052
Mots-clésAmino Acids, Cyclic, Models, Molecular, Molecular Conformation
Abstract

In order to investigate the ability of the (S)-aminobicyclo[2.2.2]octane-2-carboxylic acid 1 (H-(S)-ABOC-OH) to induce reverse turns into peptides, two model tripeptides, in which this bicyclic unit was incorporated into the second position, were synthesized and analyzed by FT-IR, CD, NMR, and X-ray studies.

DOI10.1021/ol203406v
Alternate JournalOrg. Lett.
PubMed ID22292802