| Titre | Poly(n-butyl cyanoacrylate) nanoparticles via miniemulsion polymerization. 2. PEG-based surfactants. |
| Publication Type | Journal Article |
| Year of Publication | 2009 |
| Authors | Wu, M, Dellacherie, E, Durand, A, Marie, E |
| Journal | Colloids Surf B Biointerfaces |
| Volume | 69 |
| Issue | 1 |
| Pagination | 147-51 |
| Date Published | 2009 Feb 15 |
| ISSN | 1873-4367 |
| Mots-clés | Adsorption, Dextrans, Emulsions, Enbucrilate, Molecular Conformation, Nanoparticles, Particle Size, Polyethylene Glycols, Surface Properties, Surface Tension, Surface-Active Agents |
| Abstract | This study aimed at synthesizing PEG-coated poly(n-butyl cyanoacrylate) nanoparticles by miniemulsion polymerization. Despite the high reactivity of butyl cyanoacrylate, nanoparticles were successfully obtained by miniemulsion polymerization of butyl cyanoacrylate-in-water emulsions stabilized by three PEG-based surfactants: Brij78, Brij700, and Tween80. Their physico-chemical properties were thoroughly investigated as a function of surfactant structure and concentration and discussed on the basis of results obtained from interfacial tension measurements (dodecane-water). Results clearly showed the influence of the length of the PEG part of the surfactant on the final properties of the particles. |
| DOI | 10.1016/j.colsurfb.2008.10.003 |
| Alternate Journal | Colloids Surf B Biointerfaces |
| PubMed ID | 19027270 |